Premature birth appears to weaken brain connections​

Babies born prematurely face an increased risk of neurological and psychiatric problems that may be due to weakened connections in brain networks linked to attention, communication and the processing of emotions, according to new School of Medicine research led by Cynthia Rogers, MD. 

Soldiers screened for potential vulnerability to tinnitus

Hearing loss is common for soldiers coming home from deployments to Iraq and Afghanistan, but another perhaps equally vexing problem is tinnitus, a condition that causes them to hear sound that isn’t there. Using MRI scans, researchers hope to identify differences in brain activity that will aid development of preventive strategies to alleviate the effects of tinnitus.

Brain networks may be key to stroke-related attention deficit

Areas activated by tasks designed to stimulate voluntary attentionThe first direct analysis of the interactions between two brain networks that govern visual attention may help researchers at the School of Medicine develop treatments for stroke patients with a condition known as spatial neglect. These patients have difficulty focusing on or paying attention to stimuli in the left half of their visual field.

Brain networks may be key to odd attention deficit produced by some strokes

Among the areas activated by tasks designed to stimulate voluntary attention were the intraparietal sulcus and frontal eye fields, both believed to be part of a network of neurons called the dorsal attention system.The first direct analysis of the interactions between two brain networks that govern visual attention may help researchers at Washington University School of Medicine in St. Louis develop treatments for stroke patients with a condition known as spatial neglect. These patients have difficulty focusing on or paying attention to stimuli in the left half of their visual field. They may forget to shave the left side of their face, fail to eat food on the left side of a plate or seem to be unaware that their left arm belongs to them. However, researchers have found that if they explicitly tell these people to pay attention to their left side, for a brief time they can do so.

Brain region learns to anticipate risk, provides early warnings, suggests new study in Science

Joshua Brown of WUSTLA new theory suggests that the brain may subconsciously help us avoid risky situations.While some scientists discount the existence of a sixth sense for danger, new research from Washington University in St. Louis has identified a brain region that clearly acts as an early warning system — one that monitors environmental cues, weighs possible consequences and helps us adjust our behavior to avoid dangerous situations. “Our brains are better at picking up subtle warning signs than we previously thought,” says WUSTL research psychologist Joshua Brown, co-author of a study on these findings in the Feb. 18 issue of the journal Science.

Brain region learns to anticipate risk, provides early warnings, suggests new study in Science

Joshua Brown of WUSTLA new theory suggests that the brain may subconsciously help us avoid risky situations.While some scientists discount the existence of a sixth sense for danger, new research from Washington University in St. Louis has identified a brain region that clearly acts as an early warning system — one that monitors environmental cues, weighs possible consequences and helps us adjust our behavior to avoid dangerous situations. “Our brains are better at picking up subtle warning signs than we previously thought,” says WUSTL research psychologist Joshua Brown, co-author of a study on these findings in the Feb. 18 issue of the journal Science.

Brain changes in Alzheimer’s disease

At the time of the first MRI scans, the turquoise color shows areas of the hippocampus in patients with mild Alzheimer’s disease that are shaped differently than in healthy older people. Two years later, even more changes have occurred, represented by the purple color.Even when people have no symptoms, their brains already may be dotted with the plaques and tangles that characterize Alzheimer’s disease. As treatments to halt the progress of Alzheimer’s disease appear on the horizon, scientists are looking for new ways to identify Alzheimer’s-associated changes in the brain before cognitive decline begins. By examining brain images, researchers, led by John G. Csernansky, M.D., the Gregory B. Couch Professor of Psychiatry, and Lei Wang, Ph.D., research associate in psychiatry, both at Washington University’s Silvio Conte Center for Neuroscience Research, found that the volume and shape of certain brain structures change in different patterns during Alzheimer’s disease than in healthy aging. They believe that someday using these imaging techniques may allow for earlier diagnosis of Alzheimer’s disease, preferably before the most devastating symptoms appear.