Dean David Perlmutter, MD, is aligning resources at the School of Medicine to focus on ­personalized, precision ­medicine: managing health ­instead of disease, providing the right ­treatment for the right patient, and developing drugs and other ­therapies faster and at lower cost.

Pursuing a precision paradigm

Why move from current standards of patient care to a more personalized approach to treatment? Experts at the School of Medicine describe today’s medical landscape as they plan for the care — and cures — of the future.
Timothy Ley, MD, the Lewis T. and Rosalind B. Apple Professor of Medicine, is a hematologist, oncologist and cancer biologist. For decades, the Ley lab has used mouse models of acute myeloid leukemia to establish key principles of AML pathogenesis. (Photo: James Byard)

Undaunted explorer

Timothy Ley, MD, has been investigating leukemia, particularly acute myeloid leukemia (AML), for decades. His research team now knows the mutations they need to go after ­aggressively, the nature of the ­mutations that need to be targeted and why patients relapse.
Cheryl Leyns is among the promising graduate students spread out across the School of Medicine. She works in David Holtzman’s lab, researching pathologies of Alzheimer’s disease. (Photo: James Byard)

A promising future

At Washington University, training the next generation of leaders in translational medicine is a key focus. Here, Cheryl Leyns and Phat Huynh share stories of working in the lab of David Holtzman, MD, researching pathologies of Alzheimer’s disease.