Genetic errors linked to aging underlie leukemia that develops after cancer treatment
New research by Daniel Link, MD, and colleagues at The Genome Institute at Washington University has revealed that mutations that accumulate randomly as a person ages can play a role in a fatal form of leukemia that develops after treatment for another cancer.
NIH director, Sen. Roy Blunt discuss research funding in medical school visit
U.S. Sen. Roy Blunt (left) and Francis S. Collins, director of the National Institutes of Health, visited the School of Medicine this week to talk to researchers, administrators and entrepreneurs about scientific research and the need to boost and sustain federal funding for it.
Mardis, Wilson named to endowed professorships
Elaine R. Mardis, PhD, and Richard K. Wilson, PhD, both renowned for discoveries in the field of genomics, have been named to endowed professorships. They were installed by Chancellor Mark S. Wrighton (far left), and Larry J. Shapiro, MD, executive vice chancellor for medical affairs and dean of the School of Medicine (far right).
University receives $26 million for leukemia research
The National Cancer Institute has awarded two major grants totaling $26 million to leukemia researchers and physicians at the School of Medicine. The funding has the potential to lead to novel therapies for leukemia that improve survival and reduce treatment-related side effects. Pictured are cancer cells from a patient with acute myeloid leukemia.
DNA study reveals clues to human, ape evolution
New research provides one of the most detailed and comprehensive analyses yet of the genetic diversity of endangered great apes living in the wild, revealing new clues to the evolution of apes and humans.
Scientists assemble genetic playbook for acute leukemia
A consortium of researchers led by the School of Medicine has identified virtually all of the major mutations that drive acute myeloid leukemia (AML), a fast-growing blood cancer in adults that often is difficult to treat. The dark lines in the image pictured show all of the major mutations for AML that occurred in one patient with the disease.
Hundreds of random mutations in leukemia related to aging, not cancer
Hundreds of mutations exist in leukemia cells at the time of diagnosis but nearly all occur randomly as a part of normal aging and are not related to cancer, new research at Washington University School of Medicine shows.
Wilson among most-cited authors
For the second consecutive year, Richard Wilson, PhD, director of Washington University’s Genome Institute, was named as one of the world’s most-cited scientific authors, according to Thomson Reuters Science Watch. The annual survey tracks research across various scientific disciplines to determine which papers published in the past two years were cited most often by other […]
Detailed picture of ovarian cancer emerges
School of Medicine scientists, including Richard Wilson, PhD, have completed the largest analysis to date of the genetic mutations underlying ovarian cancer.