spinal development

An X-ray of a case of scoliosis.Physicians have recognized scoliosis, the abnormal curvature of the spine, since the time of Hippocrates, but its causes have remained a mystery — until now. Researchers at the School of Medicine and collaborating institutions have discovered a gene that underlies the condition, which affects about three percent of all children. The finding lays the groundwork for determining how the genetic defect leads to the C- and S-shaped curves that characterize scoliosis.

An X-ray of a case of scoliosis.Physicians have recognized scoliosis, the abnormal curvature of the spine, since the time of Hippocrates, but its causes have remained a mystery — until now. Researchers at Washington University School of Medicine in St. Louis and collaborating institutions have discovered a gene that underlies the condition, which affects about three percent of all children. The finding lays the groundwork for determining how the genetic defect leads to the C- and S-shaped curves that characterize scoliosis.