Washington University School of Medicine in St. Louis

Max Wolfson and Amber Lin, second-year medical students, perform at a School of Medicine coffeehouse Nov. 29. Held three times a year and hosted by the school’s Arts Commission, the coffeehouses give students the opportunity to showcase musical and other talents.

The employee 2011-12 U-Pass — allowing WUSTL faculty and staff free use of Metro, the region’s public transportation system — will expire June 30. Benefits-eligible employees may request a new U-Pass for the 2012-13 fiscal year at the Parking & Transportation Services website, parking.wustl.edu/upass.htm. The new pass will be valid through June 30, 2013.

Disease-causing bacteria’s efforts to resist antibiotics may get help from their distant bacterial relatives that live in the soil, new research by Kevin Forsberg, a graduate student at Washington University School of Medicine suggests. The researchers found identical genes for antibiotic resistance in soil bacteria and in pathogens from clinics around the world.

After defeating an infection, the immune system creates a memory of the attacker to make it easier to eliminate in the future. Researchers at Washington University School of Medicine in St. Louis have discovered an important component of the immune system’s strategy for preserving such immunological memories.

An operation for preventing repeat strokes in high-risk patients has failed in a multi-institutional clinical trial, led by Colin P. Derdeyn, MD, professor of radiology at Washington University School of Medicine. Results are reported in the Journal of the American Medical Association.

Artery-opening brain stents designed to reduce high risk of repeat strokes instead significantly increased strokes and deaths, results of a multi-center clinical trial show.

A newly established fund to support innovative cancer research at the Alvin J. Siteman Cancer Center has awarded its first two $900,000 grants to high-tech efforts to undermine cancer cells’ ability to resist treatment. The awards will help scientists use genetic data to find new ways to attack treatment-resistant breast cancer and precisely target treatments for various kinds of cancer cells based on their responses to radiation therapy.

The same trait that makes a rare immune cell invaluable in fighting some infections also can be exploited by other diseases to cause harm, two new studies show. By studying the basic functions of these cells, scientists are laying the groundwork to use them to fight infections. The cells also appear to be essential for some cancer vaccines, which enlist the power of the immune system to help fight tumors.

Like explorers mapping a new planet, scientists probing the brain need every type of landmark they can get. Each mountain, river or forest helps scientists find their way through the intricacies of the human brain. Researchers at Washington University School of Medicine in St. Louis have developed a new technique that provides rapid access to brain landmarks formerly only available at autopsy.

Falls and balance problems may be early indicators of Alzheimer’s disease, researchers at Washington University School of Medicine in St. Louis report July 17, 2011, at the Azheimer’s Association International Conference on Alzheimer’s Disease in Paris.