heart disease

People with diabetes often develop clogged arteries that cause heart disease. New research at Washington University School of Medicine in St. Louis has found that when vitamin D levels are adequate in people with diabetes, blood vessels are less likely to clog. But in patients with insufficient vitamin D, immune cells bind to blood vessels near the heart, then trap cholesterol to block those blood vessels.

Zuum, a free iPad app, estimates a user’s disease risk and offers a customized plan for living a healthier life.

Researchers, led by Jean E. Schaffer, MD, at Washington University School of Medicine in St. Louis have received a $4.7 million grant from the National Heart, Lung, and Blood Institute to investigate heart disease in patients with diabetes.

Researchers at Washington University School of Medicine in St. Louis have found that problems with a digestive process in cells can clog arteries. The finding could provide a target for future therapies aimed at preventing or reversing atherosclerosis.

People with HIV often develop blood sugar and lipid problems and other metabolic complications that increase heart disease risk. New research at Washington University School of Medicine in St. Louis shows that the HIV virus and the drugs used to treat it don’t worsen heart metabolism and function in these patients. p, , {margin:0in;margin-bottom:.0001pt;font-size:12.0pt;font-family:Cambria;} div.WordSection1 {page:WordSection1;}

Bariatric surgery is not only cost-effective for treating people who are severely obese, but also for those who are mildly obese, according to a new study from Washington University School of Medicine in St. Louis. The findings support making bariatric surgery available to all obese people, the researchers say.

A fatal genetic disorder that frequently takes years to diagnose may soon be detectable with a simple blood test, researchers at Washington University School of Medicine in St. Louis and the National Institutes of Health report this week in Science Translational Medicine.

Hearts with muscle thickening (left) get less energy because of their reduced fat metabolism.”The heart is the single most energy-consuming organ per weight in the body,” says Lisa de las Fuentes, M.D. Under some conditions this energy-hungry organ is prone to defects in its energy metabolism that contribute to heart disease, according to research published in the Journal of Nuclear Cardiology by de las Fuentes and colleagues at the School of Medicine.

Echocardiograms show that the thickness of left ventricular (LV) walls in the hypertrophied heart (left) are nearly twice that of the normal heart.”The heart is the single most energy-consuming organ per weight in the body,” says Lisa de las Fuentes, M.D. Under some conditions this energy-hungry organ is prone to defects in its energy metabolism that contribute to heart disease, according to research published in the Journal of Nuclear Cardiology by de las Fuentes and colleagues at Washington University School of Medicine in St. Louis.

Poorly controlled blood glucose levels can negatively affect blood flow to the heart.In the heart muscle of type 1 diabetics, high blood glucose is a significant contributor to poorly opening vessels, or poor vasodilation, according to a study by researchers at the School of Medicine. Even administration of high levels of insulin, which usually enhances vasodilation, can’t counteract the negative effect of high glucose on the heart, and this contributes to increased plaque buildup and heart disease.