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Several of the School of Medicine’s musically talented students, faculty and staff recently performed their second annual winter concert in the lobby of the Center for Advanced Medicine. Shown are laboratory technician Rowan Karvas on clarinet and graduate student Mo Lee on piano in a performance of Paul Jeanjean’s “Arabesques.”

A Washington University in St. Louis team is participating in the modENCODE project, a massive ongoing effort to map all the elements in model organisms that affect whether genes are silenced or expressed. The work supports the more complex ENCODE project, which is tasked to map the same elements in the human genome. While the genome is the same in every cell, each cell type expresses a different set of genes. In people, moreover, roughly 95 percent of the genome is silenced. Together the projects will “put flesh on the bones” of the Human Genome Project, says team leader Sarah C.R. Elgin.