Diabetes drug safe for HIV patients, study finds

People with HIV have an elevated risk of heart attacks, diabetes and insulin problems, and there are not many drug options to prevent those problems due to concerns that they will weaken the immune system. But a new study by researchers at the School of Medicine has shown that a diabetes drug appears to be safe in patients and does not dampen their immunity.

Nanoparticles loaded with bee venom kill HIV

Nanoparticles carrying a toxin found in bee venom can destroy human immunodeficiency virus (HIV) while leaving surrounding cells unharmed, researchers at the School of Medicine have shown. The finding is an important step toward developing a vaginal gel that may prevent the spread of HIV.  Shown are nanoparticles (purple) carrying melittin (green) that fuse with HIV (small circles with spiked outer ring), destroying the virus’s protective envelope.

Powderly to lead global health initiatives​

William G. Powderly, MD, will lead global health initiatives as a newly appointed deputy director of Washington University’s Institute of Public Health. He also will serve as co-director of the Division of Infectious Diseases in the Department of Medicine at the university’s School of Medicine. ​

HIV drugs interfere with blood sugar, lead to insulin resistance

The same powerful drugs that have extended the lives of countless people with HIV come with a price — insulin resistance that can lead to diabetes and cardiovascular disease. Now, Paul Hruz, MD, PhD, and his team at Washington University School of Medicine in St. Louis have determined why that happens.

Cottler receives Marian W. Fischman Award

Linda B. Cottler, PhD, will receive the Marian W. Fischman Memorial Lectureship Award at the 72nd annual meeting of the College of Problems of Drug Dependence. The award was established to recognize the contributions of outstanding women scientists in drug abuse research. 

HIV infection prematurely ages the brain

HIV infection or the treatments used to control it are prematurely aging the brain, researchers at Washington University School of Medicine in St. Louis and the University of California-San Diego have found. Blood flow in the brains of HIV patients is reduced to levels normally seen in uninfected patients 15 to 20 years older.