Research Wire​​​​​​​​​

The latest Washington University research news


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12.18.15

Heather L. True-Krob, PhD, associate professor of cell biology and physiology, and Conrad C. Weihl, PhD, MD, associate professor of neurology, have received a five-year, $2.74 million grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health (NIH) for research titled “Chaperone Dysfunction in Myopathy: Connecting Yeast Genetics with Mouse Models.”


12.18.15

Sergej Djuranovic, PhD, assistant professor of cell biology and physiology at the School of Medicine, has received a five-year, $1.6 million grant from the National Institutes of General Medical Sciences of the National Institutes of Health (NIH) for research titled “Mechanisms for Modulation of miRNA-mediated Gene Silencing.”


12.14.15

Eugene Oltz, PhD, professor of pathology and immunology at the School of Medicine, has received a five-year, $1.9 million grant from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health (NIH) for research titled “Topological Mechanisms of DNA Break Repair in Lymphocytes.”


12.14.15

Nima Mosammaparast, MD, PhD, assistant professor of pathology and immunology at the School of Medicine, has received a five-year, $1.74 million grant from the National Institutes of Health (NIH) for research titled “Mechanism and Regulation of the DNA Alkylation Damage Response.” Mosammaparast also received a 2015 American Society for Clinical Investigation (ASCI) Young Physician-Scientist Award.


12.14.15

Ronald Jackups, MD, PhD, assistant professor of pathology and immunology and of pediatrics at the School of Medicine, and assistant medical director of the Barnes-Jewish Hospital Blood Bank and Hematology Laboratory, has received a one-year, $35,835 grant from The Foundation for Barnes-Jewish Hospital for research titled “Development of Clinical Decision Support Tools for Patient Blood Management.”


12.11.15

Richard Axelbaum, PhD, the Stifel & Quinette Jens Professor of Environmental
Engineering Science in the School of Engineering & Applied Science,
received a $123,782 grant from NASA for research titled “Flame Design: A
Novel Approach to Clean Efficient Diffusion Flames.” ​


12.11.15


Raymond Arvidson, PhD, the James S. McDonnell Distinguished University Professor in earth and planetary sciences in Arts & Sciences, received a five-year, $9,822,807 grant from NASA for a project titled “The Planetary Data System Geosciences Node at Washington University in St. Louis.”


12.4.15

Breanne Leigh Harty, a graduate student in the laboratory of Kelly Monk, PhD, assistant professor of developmental biology in the School of Medicine, has received a two-year, $56,246 predoctoral fellowship award from the National Institutes of Health (NIH) for research titled “Molecular Control of Myelinating Glial Cell Development by FBXW7.”


12.3.15

Sarah Bobmeyer, assistant director of evaluation in the Center for Public Health Systems Science at the Brown School, received $123,065 of a two-year, $500,000 grant from the Missouri Foundation for Health for her continuing project with the Institute for Public Health evaluating expansion of health coverage.


12.2.15

Jeffrey Gamble, a doctoral student in engineering, is developing a new cell culture platform that will allow biomedical engineers to better evaluate communication between immature spinal cord neurons and surviving neurons after a spinal cord injury. He works in the lab of Dennis Barbour, MD, PhD, associate professor of biomedical engineering in the School of Engineering & Applied Science, who received a two-year, nearly $250,000 grant from the University of Missouri’s Spinal Cord Injuries Research Program. For more details, visit the School of Engineering site.


11.25.15

The Institute for Public Health has awarded Public Health-Cubed (PH3) grants of $15,000 to eight projects this fall. PH3 is a rapid seed-funding mechanism to support cross-disciplinary projects from the institute’s faculty scholars. For more details, visit the Institute for Public Health site.


11.19.15

Robert Blankenship, PhD, the Lucille P. Markey Distinguished Professor of Arts & Sciences in biology, has received $45,000 of a four-year grant totaling $180,000 from the Binational Science Foundation. Blankenship joins Noam Adir, a professor at Technion – Israel Institute of Technology in research titled “Exploring and Utilizing the Remarkable Energy Transfer Characteristics of the Phycobilisome.”


11.19.15

Katharina Lodders, PhD, and Bruce Fegley, PhD, both professors of earth and planetary sciences in Arts & Sciences, received a three-year, $503,000 grant from the National Science Foundation for research titled “Abundance of the Elements and Stellar Chemistry.”


11.18.15

D.C. Rao, PhD, director of the Division of Biostatistics at the School of Medicine, professor of biostatistics, and of biostatistics in genetics and in psychiatry, has received a $3.59 million supplement from the National Heart, Lung, and Blood Institute of the National Institutes of Health (NIH) for research titled “Rare Variants for Hypertension in Taiwan Chinese.”


11.18.15

Graham Colditz, MD, DrPH, the Niess-Gain Professor of Surgery at the School of Medicine, chief of the Division of Public Health Sciences and associate director of prevention and control at Siteman Cancer Center, and Aimee James, PhD, associate professor of surgery, have received a three-year, $492,900 grant from the National Cancer Institute of the National Institutes of Health (NIH) to collaborate with the Southern Illinois University School of Medicine and its Simmon Cancer Institute, in conjunction with Washington University School of Medicine and Siteman Cancer Center, to address the needs of rural, underserved populations experiencing cancer disparities in southern Illinois. The grant is titled “Addressing Rural Cancer Disparities: A SCC-SIUSM Partnership.”

Additionally, Colditz has received a five-year, $1.55 million grant from the National Cancer Institute of NIH for work titled “Postdoctoral Training in Cancer Prevention and Control.”


11.16.15

The School of Medicine’s William Gillanders, MD, professor of surgery and vice chair for research in the Department of Surgery; Graham Colditz, MD, DrPH, the Niess-Gain Professor of Surgery, chief of the Division of Public Health Sciences and associate director of prevention and control at Siteman Cancer Center; and Timothy Eberlein, MD, the Bixby Professor of Surgery, head of the Department of Surgery, director of the Siteman Cancer Center, and the Spencer T. and Ann W. Olin Distinguished Professor, together have received a five-year, $2.75 million grant from the National Cancer Institute of the National Institutes of Health (NIH) for research titled “Surgical Oncology Basic Science and Translational Research Training Program.”


11.16.15

Baranidharan Raman, PhD, assistant professor of biomedical engineering in the School of Engineering & Applied Science, is looking to nature for clues about the sense of smell. Raman has been awarded a five-year, $600,000 Faculty Early Career Development Award (CAREER) from the National Science Foundation to understand information-processing principles in the biological sense of smell, or olfaction, and to develop bio-inspired signal processing algorithms for artificial olfaction. His project is titled “Neural Dynamics, Olfactory Coding and Behavior.” For more details, visit the engineering site.


11.12.15

Raj Jain, PhD, professor of computer science and engineering in the School of Engineering & Applied Science, has received $220,000 of a two-year grant from the National Science Foundation for research titled “CICI: Secure Data Architecture: Collaborative Research: Assured Mission Delivery Network Framework for Secure Scientific Collaboration.”


11.12.15

Yehuda Ben-Shahar, PhD, associate professor of biology in Arts & Sciences, has received additional funding of $93,999 for a grant totaling $563,999 from the National Science Foundation for research entitled “ICOB: miRNAs and the Social Regulation of Behavioral Plasticity.”


11.9.15

Marco Colonna, MD, the Robert Rock Belliveau, MD, Professor of Pathology and of medicine at the School of Medicine, has received a four-year, $1.37 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health (NIH) for research titled “CRTAM-CADM1 Interaction in the Biology of Gut Lymphocytes”; a nine-month, $103,776 grant from the NIH for research titled “Administrative Supplement to: The Role of NK-22 Cells in Anti-HIV-1 Mucosal Immunity”; a one-year, $100,000 grant from the Kenneth Rainin Foundation for research titled “Novel Adhesive Interactions Modulate T Cell Responses in IBD”; a one-year, $100,000 grant from the Cure Alzheimer’s Fund for research titled “The Role of TREML2 in Alzheimer’s Disease”; and a one-year, $50,000 grant from the NIH for research as part of the NIH AIDS Reagent Program for work titled “ILC Reagents for NIH AIDS Reagent Program.”

Colonna and Eugene Oltz, PhD, professor of pathology and immunology, together received a two-year, $419,375 grant from the National Institute of Allergy and Infectious Diseases of the NIH for research titled “Chromatin-Based Discovery of ILC Gene Regulatory Circuits.”


11.9.15

Gautam Dantas, PhD, associate professor of pathology and immunology in the School of Medicine, of biomedical engineering and of molecular microbiology, and Marcus Foston, PhD, and Tae Seok Moon, PhD, assistant professors of energy, environmental and chemical engineering in the School of Engineering & Applied Science, have received a three-year, $1.3 million grant from the U.S. Department of Energy for research titled “Systems Biology of Rhodococcus Opacus to Enable Production of Fuels and Chemicals from Lignocellulose.”

Dantas also has received a one-year, $150,000 breakthrough award from the Kenneth Rainin Foundation for research titled “Synthetic Engineering of Enhanced Fitness and Adhesion Properties in Probiotics for the Treatment of Inflammatory Bowel Disease”; was named the 57th Mallinckrodt Scholar and received a four-year, $400,000 grant from the Edward Mallinckrodt Jr. Foundation for research titled “Quantitative Modeling of Antibiotic Resistance Gene Transmission Between Human and Environmental Microbiota”; received a one-year, $152,697 grant from the National Institutes of Health (NIH) for research titled “Impact of Fecal Transplantation on Resistant Organism Carriage and the Resistome”; and received a one-year, $60,000 grant from The Foundation for Barnes-Jewish Hospital for research titled “Rabid and Accurate Sequencing-Based Diagnostics for Urinary Tract Infection.”


11.6.15

Gary J. Patti, PhD, associate professor of chemistry in Arts & Sciences, has received $199,013 of a three-year grant from the National Institutes of Health (NIH)’s National Cancer Institute for research entitled “Cell-Specific Isotope Labeling to Track Intercellular Metabolite Exchange in Cancer.”


11.6.15

Robert G. Kranz, PhD, professor of biology in Arts & Sciences, has received $338,675 in continuing funding as part of a 25-year grant, through August 2019, from the National Institutes of Health (NIH)’s National Institute of General Medical Sciences for research titled “Cytochrome c Biogenesis.”


11.4.15

Lori Markson, PhD, associate professor of psychological and brain sciences in Arts & Sciences, will pursue research on the development of optimism in children as one of 18 projects funded recently under a national research program sponsored by the John Templeton Foundation. Markson and postdoctoral researcher Laura Hennefield will explore how optimism develops in children, including a theory that suggests optimism emerges in early childhood and its development is influenced by early experiences, especially negative life events.


10.27.15

James Janetka, PhD, associate professor of biochemistry and molecular biophysics, along with Henry Han, PhD, assistant professor of neurological surgery, both in the School of Medicine, have received a one-year, $25,000 grant from the University Research Strategic Alliance program for research titled “Selective Diagnostic Imaging Agents for Cerebral Amyloid Angiopathy Plaques in Alzheimer’s Disease.”


10.27.15

Michael E. Wysession, PhD, professor of earth and planetary sciences in Arts & Sciences, has received $96,516 of a three-year grant totaling $374,999 from the National Science Foundation for research titled “Mapping the Middle of the Mantle-Core Dynamic.”


10.27.15

Himadri Pakrasi, PhD, the Myron and Sonya Glassberg/Albert and Blanche Greensfelder Distinguished University Professor of biology in Arts & Sciences, has received $300,000 in the final year of a $2,498,500 seventeen-year grant from the U.S. Department of Energy for research titled “Redox Factors in the Thylakoid Lumen for Protection and Repair of the Photosynthetic Apparatus.”


10.21.15

Christine Kirmaier, PhD, research professor of chemistry in Arts & Sciences, has received $350,000 in the final year of an overall seven-year, $1.4 million grant from the U.S. Department of Energy for research titled “Controlling Electron Transfer Pathways in Photosynthetic Reaction Centers.”


10.20.15

Jeremy Buhler, PhD, professor of computer science and engineering in the School of Engineering & Applied Science, has received a two-year, $249,966 grant from the National Science Foundation to develop new designs, techniques and implementation strategies to make programs on Single Instruction, Multiple Data computer processors more efficient. Buhler will work with Roger Chamberlain, PhD, also a professor of computer science and engineering, to build software components for Graphics Processing Units that perform all necessary remapping operations behind the scenes, allowing the programmer to focus on describing only the interesting parts of a computation. For more details, visit the School of Engineering site.



10.19.15

Ramaswamy Govindan, MD, professor of medicine, and Mark Watson, MD, PhD, associate professor of pathology and immunology at the School of Medicine and director of the Tissue Procurement and Multiplexed Gene Analysis Laboratories, have received a five-year, $1.55 million grant from the National Cancer Institute of the National Institutes of Health (NIH) for research titled “Genomic Harbingers of Brain Metastasis in Non-Small Cell Lung Cancer.”


10.13.15

Monika Vig, PhD, assistant professor of pathology and immunology at the School of Medicine, has received a four-year, $792,000 grant from the American Cancer Society for research titled “Molecular Dissection of Store-Operated Calcium Entry in Cancer Metastasis”; and a five-year, $1.9 million grant from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health (NIH) for research titled “CRAC Channel Components and Molecular Basis of Store-Operated Calcium Entry.”


10.13.15

Hani Suleiman, MD, PhD, instructor in pathology and immunology at the School of Medicine, has received a three-year, $225,000 grant from the NephCure Foundation for research titled “A Novel Superresolution Imaging Approach of Glomerular Disease.”


10.6.15

Richard Axelbaum, PhD, the Stifel & Quinette Jens Professor of Environmental Engineering Science in the School of Engineering & Applied Science, has received a two-year, $996,652 grant from the U.S. Department of Energy’s National Energy Tech Lab for “Integrated Flue Gas Purification and Latent Heat Recovery for Pressurized Oxy-Comubstion.”


10.5.15

Jr-Shin Li, PhD, Das Family Career Development Associate Professor of electrical and systems engineering in the School of Engineering & Applied Science, and associate professor of biology and biomedical sciences in Arts & Sciences, has received a three-year, $280,000 grant from the National Science Foundation for “Optimal Pulse Design in Quantum Control.”

10.5.15

Erik Herzog, PhD, professor of biology in Arts & Sciences, and Jeanne Nerbonne, PhD, professor of medicine at the School of Medicine, have received $60,000 in the third year of a four-year grant expected to total $348,000 from the National Institutes of Health’s National Institute of General Medical Sciences for “Neuronal Excitability in the Regulation of Circadian Rhythms.”


10.5.15


Yixin Chen, PhD, associate professor of computer science and engineering in the School of Engineering & Applied Science, has received a three-year, $248,790 grant from the National Science Foundation for “III: Small: Collaborative Research: Towards Interpretable Machine Learning.”

9.29.15

​​Steven George, MD, PhD, the Elvera & William Stuckenberg
Professor of Technology & Human Affairs and chair of the Department of Biomedical Engineering in the School
of Engineering & Applied Science, has received a grant of $152,500 in the fourth year of a five-year grant with an expected total of $884,102 from the National Institutes of Health’s National
Center for Advancing Translational Sciences
for a project titled “An Integrated In
vitro Model of Perfused Tumor and Cardiac Tissue.”


9.29.15

​Steven George, MD, PhD, the Elvera & William Stuckenberg
Professor of Technology & Human Affairs and chair of the Department of Biomedical Engineering in the School
of Engineering & Applied Science, has received a grant of $228,707 as
part of a five-year grant that totals $1,112,809 from the National Institutes of Health’s National
Center for Advancing Translational Sciences
for a project titled “Linking DDR2 Expression, the
Cancer-associated Fibroblast and Angiogenesis in the Tumor Microenvironment.”​


9.29.15

​Ross C.
Brownson
, PhD, the Bernard Becker Professor in the Brown School, has received $166,216 in the second year of a grant from the National Institutes of Health’s National
Cancer Institute
for “A
Cross-Country Comparison of Evidence-Based Prevention of Cancer.”



9.29.15
Roch Guerin, PhD, Harold B. and Adelaide G. Welge Professor of Computer Science, Chenyang Lu, PhD, Fullgraf Professor, and Christopher Gill, DSc, professor of computer science, all in the School of Engineering & Applied Science, have received a four-year, $602,228 grant for “NeTS: Medium: Provisioning, Enforcing, and Pricing Temporal Service Differentiation in Virtualized Networked Environments” from the National Science Foundation.

9.29.15
E.A. Quinn, PhD, assistant professor of anthropology, and Geoff Childs, PhD, associate professor of sociological anthropology, both in Arts & Sciences, have received a three-year, $354,999 grant from the National Science Foundation for research titled “Infant Growth, Milk Composition, and Maternal Energetics in a High-altitude Environment.”

9.29.15
John Shareshian, PhD, professor of mathematics in Arts & Sciences, has received a four-year, $180,997 grant from
the National Science Foundation for research titled “Topological, Enumerative and
Algebraic Combinatorics.”


9.29.15

Lucia Strader, PhD, assistant professor of biology in Arts & Sciencs, has received $301,188 in the first installment of an expected four-year grant from the National Institutes of Health’s National Institute of General Medical Sciences for research titled “Regulation of Auxin Response Factor Activity in Arabidopsis.”


9.29.15

ShiNung Ching, PhD, assistant professor of electrical and systems engineering in the School of Engineering & Applied Science, will use a three-year, $374,643 grant from the National Science Foundation to develop and analyze mathematical models of brain networks. Specifically, Ching will use these models to investigate how particular features of brain networks may enable processing of information, such as sounds and visual cues from the environment. For more details, visit the School of Engineering site.



9.23.15

Richard J. Perrin, MD, PhD, assistant professor of pathology and immunology; co-investigator Jacqueline E. Payton, MD, PhD, assistant professor of pathology and immunology; co-investigator Chengjie Xiong, PhD, professor of biostatistics and of neurology; and collaborator R. Reid Townsend, MD, PhD, professor of medicine and of cell biology and physiology, all in the School of Medicine, have received a three-year, $250,000 grant from the BrightFocus Foundation for research titled “Novel CSF Biomarkers in Familial Alzheimer’s Disease.”



9.17.15

​Kevin D. Moeller, PhD, professor of chemistry in the College of Arts & Sciences, has received a three-year, $465,000 grant from the National Science Foundation for research entitled “Intramolecular Anodic Olefin Coupling Reactions.”


9.17.15

Liviu M. Mirica, PhD, associate professor of chemistry in the College of Arts & Sciences, has received a $289,750 grant toward an expected total of $1,448,750 over five years from the National Institutes of Health for research entitled “Novel Bifunctional Chemical Agents as Theranostic Tools for Amyloid Diseases.”


9.17.15

Kater Murch, PhD, assistant professor of physics in the College of Arts & Sciences, has received a three-year, $662,027 grant from the John Templeton Foundation for research entitled “Structure of Time in Quantum Mechanics.” The purpose of this research is to investigate the origins and degree of time symmetry in continuously measured quantum systems, and to examine the extent to which quantum systems and measurements validate or question the notion of determinism to help elevate the debate on time symmetry and the causal nature of the quantum world.​


9.15.15

Scott A. Mangan, PhD, assistant professor of biology in Arts & Sciences, received $86,808 of an expected three-year, $163,739 grant from the National Science Foundation to continue his study “Collaborative Research: Genetic Diversity, Resistance Genes and Negative Density Dependence in Tropical Tree Seedling Dynamics.”


9.15.15

Liviu M. Mirica, PhD, associate professor of chemistry in Arts & Sciences, received continuing funding as part of a five-year, $890,000 grant from the U.S. Department of Energy for his study “Novel Redox Catalysts for Greenhouse Gases Utilization.” Mirica’s work looks at the conversion of methane into liquid fuels, which could allow for a more efficient use of natural gas reserves as inexpensive energy resources.


9.15.15

Kenneth F. Kelton, PhD, the Arthur Holly Compton Professor of Arts & Sciences, received a three-year, $408,015 grant from the National Science Foundation to continue his work on the “Elastic and Inelastic Scattering Studies of Supercooled Metallic Glass-forming Liquids — the Connection Between Ordering and Fragility.” Kelton’s work aims to understand the process of glass formation, which remains a key unsolved problem for scientists.


9.14.15

I-Ting Angelina Lee, PhD, assistant professor of computer science and engineering, and Kunal Agrawal, PhD, associate professor of computer science and engineering, both in the School of Engineering & Applied Science, have received a three-year, $449,947 grant from the National Science Foundation for research titled “SHF: Small: Locality-Aware Concurrency Platforms.”


9.14.15

Anne Hofmeister, PhD, research professor of earth and planetary sciences in Arts & Sciences, has received a three-year, $65,423 grant from the National Science Foundation for research titled “Collaborative Research: Thermal Structure of Continental Lithosphere Through Time.”

9.14.15

Hani Zaher, PhD, assistant professor of biology in Arts & Sciences, has received $268,008 of what’s expected to be a a five-year, $1.47 million grant from the National Institutes of Health for “The Role of Ribosome in Determining the Fate of Damaged MRNA.”

9.14.15

Roch Guerin, PhD, Harold B. and Adelaide G. Welge Professor of Computer Science in the School of Engineering & Applied Science, and Fred Prior, PhD, professor of radiology at the School of Medicine, have received a two-year, $475,590 grant from the National Science Foundation for “CC*DNI Networking Infrastructure (Campus Cyberinfrastructure-Data, Networking, and Innovation): Washington University Research Network.”

9.14.15

Christine Floss, PhD, research professor of physics in Arts & Sciences, has received renewal of a two-year, $60,000 grant from NASA for “Atom-Probe Studies of the Origins of Meteoritic Nanodiamonds and Silicon Carbide.”


9.14.15

Sarah C.R. Elgin, PhD, the Viktor Hamburger Professor of Arts & Sciences, has received a three-year, $544,394 grant from the National Science Foundation for “The Drosophila Dot Chromosome: Gene Expression in the Context of Repetitious DNA.”


9.10.15

Sanmay Das, PhD, associate professor of computer science and engineering in the School of Engineering & Applied Science, received a three-year, $429,600 grant from the National Science Foundation to combine an interdisciplinary mix of computer science, economics and operations research, including computational game theory and multi-agent simulation, to model the dynamics of competing platforms in the financial markets, kidney exchange and e-commerce searches. For more details, visit the School of Engineering.


9.10.15

Viktor Gruev, PhD, associate professor of computer science and engineering in the School of Engineering & Applied Science, has received a one-year, $299,857 grant from the Air Force Office of Scientific Research to develop a bio-inspired, low-noise spectral-polarization imaging system. This instrument’s capabilities are based on the vision of the mantis shrimp, which has among the most sophisticated vision of all animals. For more details, visit the School of Engineering.


9.9. 15

Alexander S. Bradley, PhD, assistant professor of earth and planetary sciences in Arts & Sciences, has received a $269,829 grant, over two years, from the National Science Foundation for “Collaborative Research: Experimental Calibration of the Isotopic Content of Marine Sulfate.”


9.4.15

Dave Spencer, MD, PhD, instructor in pathology and immunology at the School of Medicine, has received a one-year, $91,500 Leukemia Specialized Program of Research Excellence (SPORE) grant for research titled “HOX Gene Regulation in Hematopoiesis and AML.”

9.1.15

Jr-Shin Li, PhD, associate professor of electrical and systems engineering in the School of Engineering & Applied Science, has received a three-year, $476,658 grant from the National Science Foundation to develop a framework for optimal control of the dynamics in the brain’s networks through neurostimulation. Innovative technology using neurostimulation has created new treatment options for patients with neurological diseases such as Parkinson’s disease, tremors or chronic pain. To read more, visit the School of Engineering.

8.31.15

Lan Yang, PhD, the Edwin H. & Florence G. Skinner Professor in the School of Engineering & Applied Science, has been awarded $250,000 over three years from the National Science Foundation for “Collaborative Research: Thin-Film Chalcogenide Glass Materials for High-Quality Integrated Photonics.”

8.31.15

Srikanth Singamaneni, PhD, associate professor of mechanical engineering and materials science in the School of Engineering & Applied Science, has been awarded $450,000 over three years from the U.S. Air Force Office of Scientific Research for “Probing Biotic/Abiotic Interfaces at the Nanoscale Using Limited Proteolysis and Chiral Plasmonics.”



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