aging

A new study raises the intriguing possibility that drugs prescribed to lower cholesterol may be effective against macular degeneration, a blinding eye disease. Researchers at Washington University School of Medicine in St. Louis have found that age-related macular degeneration shares a common link with atherosclerosis. Both problems have the same underlying defect: the inability to remove a buildup of fat and cholesterol.

In the decades ahead, China will have a very large older population, with many older adults who are relatively healthy and interested in being actively engaged in their communities. Contributions of older adults will be necessary for social and economic development of families, communities and society. Peking University Press recently published Productive Aging in the World: Toward Evidence-Based Practice and Policy. The book is the result of a conference on productive aging in August 2011 at Peking University, co-organized by the Center for Social Development (CSD) at Washington University in St. Louis, Hong Kong Polytechnic University, and Peking University in Beijing.​

Hundreds of mutations exist in leukemia cells at the time of diagnosis but nearly all occur randomly as a part of normal aging and are not related to cancer, new research at Washington University School of Medicine shows.

John C. Morris, MD, the Harvey A. and Dorismae Hacker Friedman Distinguished Professor of Neurology and director of the Alzheimer’s Disease Research Center, will deliver the 2012 Friedman lecture at 3 p.m. April 30, in Graham Chapel. His lecture is titled “The Aging Mind: Realities and Myths.”

Americans are remaining in the workforce longer and many are changing or advancing their careers well past age 40. “With this trend towards working longer, educational institutions have been trying to figure out their role in keeping up with the needs of our aging society,” says Nancy Morrow-Howell, PhD, the Ralph and Muriel Pumphrey Professor of Social Work at the Brown School at Washington University in St. Louis. The Brown School decided to study the experiences of their students who came to get their MSW after the age of 40. The survey focuses on pathways to graduate school, their experience in the classroom as well as field, and their post-MSW careers. Morrow-Howell says that these results can be applied to other graduate programs, particularly in fields that may face labor shortages in the future, such as education, health and social services.

Worldwide, people aged 60 and above will comprise 13.6 percent of the population by 2020, and 22.1 percent of the population by 2050. China is the most rapidly aging country with older adults making up 13 percent of their population. “All countries will need to develop policies and programs that support productive engagement during later life,” says Nancy Morrow-Howell, PhD, the Ralph and Muriel Pumphrey Professor of Social Work at Washington University in St. Louis. “There is evidence that productive engagement in later life benefits both older adults and society at large. Expanding opportunities for productive engagement may increase the health and well-being of the older population. At the same time, older adults can be a valuable resource for growth in volunteering, civic service, caregiving, employment, and social entrepreneurship.”

Nutrition and longevity researchers, including Luigi Fontana, MD, PhD, have found more evidence that eating less may help people live longer. They report that individuals who significantly reduce their calorie intake have lower core body temperatures. Mice and rats consuming fewer calories also have lower core body temperatures, and they live significantly longer than littermates eating a standard diet. 

Neurologists finally have an answer to one of the most important questions about Alzheimer’s disease: Do rising brain levels of a plaque-forming substance mean patients are making more of it or that they can no longer clear it from their brains as effectively? A new study by Randall Bateman, MD, assistant professor of neurology, shows clearance is impaired in Alzheimer’s patients.

Walking, jogging and other forms of regular aerobic exercise may actually ward off the onset of Alzheimer’s disease pathology in the brain, suggests newly published research from Washington University in St. Louis.  

The protein SIRT1 in the brain is tied into a mechanism that allows animals to survive when food is scarce, according to a new study at Washington University School of Medicine in St. Louis. The research suggests that SIRT1 may be involved with the life span-increasing effect of low-calorie diets, they report.