Two-pronged immunotherapy eliminates metastatic breast cancer in mice
Researchers at the School of Medicine have identified a way to sensitize metastatic breast cancer that has spread to bone to immunotherapy.
Possible treatment strategy identified for bone marrow failure syndrome
School of Medicine researchers have identified a possible treatment strategy for some bone marrow failure syndromes. These syndromes lead to an increased risk of developing dangerous infections, anemia and an increased risk of blood cancers.
Cells take on dual identities
Cells migrate to different tissues for a variety of reasons, including organ development, tissue repair and the spread of cancer. Researchers led by Amit Pathak at the McKelvey School of Engineering have found unexpected activity in the nucleus of healthy cells that provides new insight into cell mechanics.
Medicaid expansion improves childhood cancer survival
Medicaid expansion may improve outcomes for children with cancer, finds a new analysis from the Brown School and the School of Medicine. Researchers found there was a 1.5% increase in overall survival after 2014 in states that expanded access to Medicaid compared with states that did not.
Cancer patients who don’t respond to immunotherapy lack crucial immune cells
Researchers at Washington University School of Medicine have discovered that the difference between cancer patients who do and do not respond to immunotherapy may have to do with a particular immune cell. The findings could extend the lifesaving benefits of immunotherapy to more patients.
Computer model IDs roles of individual genes in early embryonic development
Software developed at Washington University School of Medicine can predict what happens to complex gene networks when individual genes are disrupted in specific ways.
Thompson receives National Cancer Institute grant to study cancer patients, caregivers
Tess Thompson, research assistant professor at the Brown School at Washington University in St. Louis, has received a five-year grant from the National Cancer Institute of the National Institutes of Health (NIH) to study unmet social needs of cancer patients and their caregivers, with the ultimate aim of improving outcomes for both.
Patients with brain cancer may benefit from treatment to boost white blood cells
A new study led by the School of Medicine reveals at least one cause of low white blood cell counts in patients treated for glioblastoma and demonstrates a potential treatment strategy that improves survival in mice.
Power of cancer drugs may see boost by targeting newly ID’d pathway
Researchers at the School of Medicine have identified a previously unknown signaling pathway cells use to protect their DNA while it is being copied. The findings suggest a way that could boost the potency of cancer therapeutics.
Quality of treatment for lung cancer varies widely across US
A new study by researchers at Washington University School of Medicine found that the quality of care for lung cancer in the U.S. varies widely. The findings show that high-quality care is associated with improved overall survival rates among patients with lung cancer.